SEGGER J-Link
The industry standard. Best flash speed, widest target support, excellent software (J-Link GDB Server, Ozone, J-Flash). The PLUS model with USB High Speed is significantly faster than the BASE.
Best for: Professional development, production programming, anyone willing to pay for the best tooling.
Drawbacks: Expensive. Licence restrictions — the EDU version can't be used commercially. The J-Link OB (on-board) on eval boards is locked to that board's chip vendor.